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Thriving by nature

Sensorium embraces and decodes the complexities of human biology and nature to develop breakthrough medicines for people suffering from brain and mental health conditions.

Thriving by nature

Sensorium embraces and decodes the complexities of human biology and nature to develop breakthrough medicines for people suffering from brain and mental health conditions.

Leveraging millennia of human insight and cutting edge AI, we’re re-engineering molecules that co‑evolved with people to advance mental & brain health.

Coevolved chemistry

We begin with bio‑actives that history already proved compatible with human biology.

Expert curation

Neuroscientists and chemists triage signals from ethnobotany, clinic, and omics.

AI amplification

Graph learning connects hidden compound‑target links; generative models propose optimized analogs.

Our discovery platform SensAI holistically integrates comprehensive biological data to identify compounds with a high probability of clinical success.

Social anxiety disorder

SENS-01

Clinical candidate

Drug-resistant epilepsy + anxiety

SENS–03

Lead candidate

Alzheimer’s-related cognition

SENS–08

Hit identification

Social anxiety disorder

SENS–01

Clinical candidate

Drug-resistant epilepsy + anxiety

SENS–03

Lead candidate

Alzheimer’s-related cognition

SENS–08

Hit identification

Sensorium is led by executives and advisors with a record of innovation, a drive to explore, and a vision for mental health evolution.

Jacob Hooker, PhD

Cofounder and CEO

Jacob's boundless curiosity and enthusiasm inspire those around him to explore new ideas, challenge convention, and make things that matter.

Simba Gill, PhD

Executive Chair

We’re lucky to have Simba’s unmatched energy and depth—four decades of biotech leadership distilled into clear vision, unshakable optimism, and the kind of passion that lifts everyone around him.

Jeffrey Brown, PhD, MBA

Chief Science Officer

Jeffery brings a rare blend of scientific fluency and operational precision—he makes complex things simple, keeps us grounded, and always gets it done without drama.

Pranav Tadi, MBA

Head of Finance

From day one, Pranav has been our calm center—sharp, strategic, and unfailingly reliable, with an instinct for what’s around the corner and the courage to act on it.

Sam Rasty, PhD, MBA

Chief Business Officer

Sam’s network seems to know no bounds, but what makes him invaluable is his positivity and grace—he brings people in, builds momentum, and opens doors that matter.

Rolando Gutierrez-Esteinou, MD

Chief Medical Officer

Rolando sees both data and people clearly—his clinical insight, design sense, and grounded empathy as a psychiatrist make our science real and our trials smarter.

Sensorium Therapeutics is a preclinical biotechnology company developing mental health treatments that are derived from nature, mechanistically driven, clinically precise, and designed to help people thrive. Its proprietary SensAI™ platform integrates artificial intelligence, chemistry, and neuroscience to mine more than 50 million curated relationships across biology, pharmacology, clinical outcomes, and human experience to unlock broader and derisked starting points for CNS drug discovery. SensAI has produced three differentiated programs in under three years—led by SENS-01, a first-in-class treatment for anxiety—and built a robust IP estate extending into the 2040s.

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